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You play as Alyx Vance, humanity’s last hope for survival. Since the Black Mesa incident, the Cartel's control over the planet has only tightened, with the remaining population confined to cities. Among them are two of Earth's greatest scientists: your father, Dr. Eli Vance, and you. The game tells the story of an impossible fight against a cruel group of extraterrestrials known as the Cartel, waging war on humanity.